About Vinyl Magnesium Bromide
Product: Vinyl Magnesium bromide 1.0M In THF
Cas.No. 1826-67-1
Molecular Weight 131.25
Density 0.981 g/mL at 25 C
concentration 1.0 M in THF
Note: Storage below 25C otherwise may form solid nature. Warm gently to redissolve clear solution
Exceptional Reactivity for Advanced SynthesisVinyl Magnesium Bromide is celebrated for its high reactivity in Grignard reactions, making it indispensable in the preparation of complex organic molecules. Its quick and selective addition to carbonyl compounds allows chemists to construct secondary and tertiary alcohols and ketones with precision.
Storage and Safety PrecautionsDue to its violent reactivity with water and poisonous nature, Vinyl Magnesium Bromide must be handled under strict moisture-free conditions and stored under an inert atmosphere. Users must wear appropriate protective equipment and maintain storage stability by keeping it sealed and protected from air and moisture.
Versatile Uses in Organic SynthesisThis reagent is especially valued in laboratories and industries for its ability to introduce vinyl groups into molecules, which is crucial in synthesizing advanced pharmaceuticals, agrochemicals, and specialty chemicals. Its formulationtypically a 2.0 M solution in THFensures consistent performance and straightforward handling.
FAQs of Vinyl Magnesium Bromide:
Q: How should Vinyl Magnesium Bromide be stored to ensure maximum shelf life?
A: To preserve its stability, Vinyl Magnesium Bromide must be stored in a tightly sealed container, away from moisture, ideally under an inert atmosphere such as nitrogen or argon. This prevents its violent reaction with water and maintains its potency for extended periods.
Q: What is the primary benefit of using Vinyl Magnesium Bromide in organic synthesis?
A: The key advantage of Vinyl Magnesium Bromide is its effectiveness as a Grignard reagent, enabling the formation of secondary and tertiary alcohols, ketones, and a broad range of valuable organic compounds, which are essential in research and industrial chemistry.
Q: When is Vinyl Magnesium Bromide typically used during the synthetic process?
A: This reagent is introduced during the nucleophilic addition step to carbonyl compounds, often during the main or late stages of organic synthesis, when specific functionalizationsuch as the addition of vinyl groupsis required.
Q: Where can Vinyl Magnesium Bromide be sourced in India?
A: Vinyl Magnesium Bromide is available through several distributors, manufacturers, suppliers, and traders in India. Prospective buyers should ensure they are sourcing from reputable chemical suppliers who comply with stringent safety and quality standards.
Q: What are the key safety precautions when handling this chemical?
A: Due to its toxic and highly reactive nature, appropriate protective gear must be worn, and all work should be done in a well-ventilated fume hood. Direct contact with water or moisture must be strictly avoided, and emergency protocols should be accessible.
Q: How is Vinyl Magnesium Bromide typically supplied for laboratory use?
A: It is most often supplied as a 2.0 M solution in tetrahydrofuran (THF) or diethyl ether, which offers stability for shipping, storage, and practical use in controlled laboratory settings.