About Isopropylmagnesium chloride solution 2.0 M in THF
Synonym(s):Chloro 1-methylethyl magnesium, Chloroisopropylmagnesium, Isopropylmagnesium chloride, iPrMgClLinear Formula:(CH3)2CHMgClCAS Number:1068-55-9Molecular Weight:102.85Key FeaturesThis isopropylmagnesium chloride solution is offered as a 2.0 mol/L concentration in THF, making it ideal for laboratory synthesis requiring precision. Its moisture-sensitive and highly flammable nature necessitates strict adherence to safety protocols, ensuring effective and reliable chemical reactions. The sealed packaging protects against air and moisture contamination during storage and transport.
Safe Handling and StorageUse this product exclusively in a fume hood, wearing appropriate protective equipment. The solution should always remain in airtight containers under inert gas, such as argon or nitrogen, and be stored in a cool, dry location. Moisture or air exposure causes rapid decomposition and loss of reactivity, so adherence to recommended storage procedures is essential.
Applications in SynthesisAs a Grignard reagent, this solution is crucial in forming carbon-carbon bonds. Its high reactivity allows chemists to efficiently synthesize complex molecules, intermediates, and pharmaceuticals. The reagent's consistency and purity contribute to reproducible results in demanding laboratory applications.
FAQ's of Isopropylmagnesium chloride solution 2.0 M in THF:
Q: How should Isopropylmagnesium chloride solution be handled and stored to maximize its shelf life?
A: This solution must be handled in a well-ventilated fume hood, wearing full protective equipment. Always keep the container airtight and store it under an inert atmosphere, such as argon or nitrogen, in a cool, dry place. Avoid exposure to moisture, air, and extreme temperatures to maintain stability for up to 12 months.
Q: What are the main applications and benefits of using this Grignard reagent in synthesis?
A: Isopropylmagnesium chloride solution is primarily used to add isopropyl groups in organic chemical synthesis, particularly in the formation of carbon-carbon bonds. Its benefits include high reactivity, consistent results, and usefulness in pharmaceuticals and organic intermediate production.
Q: When is it appropriate to use this product in laboratory settings?
A: This reagent is suitable when performing organic synthesis that requires forming isopropyl-containing compounds, especially for creating pharmaceuticals and specialized organic molecules. Use it where controlled Grignard reactions and high reagent purity are essential.
Q: Where should this solution not be used or exposed?
A: Avoid using or opening the product outside of a chemical fume hood. It should never be exposed to air, moisture, strong oxidizers, acids, or used in incompatible environments without proper precautions, as these can lead to hazardous decomposition or diminished reactivity.
Q: What precautions are necessary during the handling process of this compound?
A: Always wear eye protection, gloves, and lab clothing. Handle the solution only in a fume hood to avoid inhalation and exposure, and never allow skin contact. Ensure that all solvents and storage vessels are dry, and use tools and equipment compatible with Grignard reagents to prevent unwanted side reactions.
Q: How does this product benefit laboratory synthesis compared to other Grignard reagents?
A: This reagent offers precise isopropyl transfer, high purity, and reliably controlled reactivity, making it preferable when sensitive, selective transformations are necessary. Its preparation in THF also improves solubility and handling compared to some alternatives, contributing to reproducible and high-yielding results.