HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium)

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HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium)

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MOQ : 100 Liters

HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium) Specification

Taste
Odorless

CAS No
148893-10-1

Poisonous
Non-poisonous

Molecular Weight
380.23 g/mol

Properties
Highly efficient coupling reagent for peptide synthesis

Molecular Formula
C10H15F6N6OP

Application
Peptide synthesis, chemical research

Shape
Crystalline

Product Type
Pharmaceutical Intermediate / Reagent

Ph Level
Neutral

Solubility
Soluble in DMF, DMSO, acetonitrile

Physical Form
Powder

HS Code
29349900

Usage
Used as a peptide coupling reagent

Melting Point
160-165C

Smell
Odorless

Ingredients
Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium

Grade
Analytical / Laboratory

Purity
99%

Appearance
White to off-white crystalline powder

Structural Formula
See image: https://cpimg.tistatic.com/9268580/s/4/HATU-Hexafluorophosphate-Azabenzotriazole-Tetramethyl-Uronium-.jpg

Shelf Life
2 Years

Storage
Store in cool, dry place tightly closed

Formulation
Pure, not blended

Sensitivity
Moisture sensitive

Handling Precautions
Avoid contact with skin and eyes, use in well ventilated area

Transport Information
Non-dangerous goods

Synonyms
O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

Packaging
25g, 100g, 500g bottle

Stability
Stable under recommended storage conditions

Hazard Statement
Not classified as hazardous material under GHS

HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium) Trade Information

Minimum Order Quantity
100 Liters

Packaging Details
hdpe tin

Main Domestic Market
South India

About HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium)

Molecular Weight:380.23

CAS Number:148893-10-1

Synonym(s):

1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate, N-[(Dimethylamino)-1H-1,2,3-triazolo-[4,5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide

Empirical Formula (Hill Notation):

C₁₀H₁₅F₆N₆OP

Highly Efficient Peptide Coupling Reagent

HATU stands out as a top-tier reagent for peptide synthesis, providing rapid and reliable coupling with exceptional yields. Its efficiency minimizes side reactions during amide bond formation, which is essential for producing high-purity peptides in research and analytical labs.

Safe and Convenient Usage

Despite its robust coupling properties, HATU is not classified as hazardous under GHS and does not pose significant transport or handling risks. For professional use, standard safety precautions such as working in well-ventilated areas and avoiding skin or eye contact are recommended.

Stable and Flexible Packaging Options

Available in 25g, 100g, and 500g bottles, HATU is stable when stored tightly sealed in a cool, dry environment. Its two-year shelf life ensures flexibility for laboratories with varying or long-term project requirements, maintaining its high performance throughout its storage period.

FAQ's of HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium):

Q: How should HATU be handled during laboratory procedures?

A: HATU should be handled in a well-ventilated area, and direct contact with the skin and eyes should be avoided. Since it is moisture sensitive, ensure the bottle is tightly closed when not in use and use personal protective equipment as appropriate.

Q: What is the primary use of HATU in research applications?

A: HATU is primarily used as a peptide coupling reagent for efficient amide bond formation during peptide synthesis. Its ability to deliver high yields with minimal side reactions makes it highly valuable in chemical and analytical research.

Q: When should HATU be stored to preserve its efficacy?

A: HATU should be stored in a cool, dry place with the container tightly closed. Proper storage conditions ensure that its shelf life extends up to two years, maintaining its coupling performance throughout this period.

Q: Where can HATU be purchased for laboratory use in India?

A: HATU can be sourced from authorized distributors, manufacturers, suppliers, and traders across India who specialize in laboratory-grade reagents and chemicals. Ensure you select a reputable supplier for genuine, high-purity material.

Q: What process is followed when using HATU for peptide synthesis?

A: Typically, HATU is dissolved in solvents like DMF, DMSO, or acetonitrile and combined with the appropriate amino acid substrates under controlled conditions. It facilitates efficient coupling, resulting in rapid amide bond formation with minimal by-products.

Q: What are the benefits of choosing HATU over other coupling reagents?

A: HATU offers high coupling efficiency, minimal side reactions, and is less hazardous in terms of transport and storage. Its ease of handling and power make it an ideal choice for both routine and high-precision peptide synthesis projects.

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