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N Butyl Lithium

Name: N Butyl Lithium
Brand: SYMAX LABORATORIES PRIVATE LIMITED
Price: 2500 INR
Availability: InStock

Price 2500 INR/ Kilograms

Get a Price/Quote

MOQ : 100 Kilograms

N Butyl Lithium Specification

CAS No
109-72-8

Product Type
Chemical Compound

Application
Used as strong base and nucleophile in organic synthesis, polymerization initiator, deprotonation and metalation reactions

Appearance
Colorless to yellowish clear liquid

Smell
Solvent-like

Shape
Liquid in container

Structural Formula
Butyl group bonded to Lithium (CH3CH2CH2CH2Li)

Purity
1.6 M in hexane (typical), other concentrations available

EINECS No
203-699-2

Grade
Industrial Grade

Solubility
Soluble in organic solvents (hexane, ether); reacts with water

Shelf Life
Two years in unopened original packaging, if stored properly

Ingredients
n-Butyl Lithium, hydrocarbon solvent (usually Hexane or Heptane)

Molecular Weight
64.06 g/mol

Molecular Formula
C4H9Li

Poisonous
YES

Ph Level
Strongly basic (not measurable in traditional sense)

Physical Form
Liquid

HS Code
2931 90 00

Properties
Highly reactive organolithium reagent; pyrophoric in air; strong nucleophile; reacts violently with water.

Usage
Organometallic laboratory synthesis, pharmaceutical intermediates, specialty chemicals manufacturing

Density
0.68 Gram per cubic centimeter(g/cm3)

Storage
Inert atmosphere (nitrogen/argon), dry, tightly sealed container, away from heat and moisture

Melting Point
-130C (approx., depends on concentration)

Packaging
Sealed bottles, cylinders, or drums under inert gas (size varies depending on supplier)

Flash Point
Highly flammable, pyrophoric-can ignite spontaneously in air

Handling Precautions
Handle under inert gas using appropriate PPE (gloves, goggles, lab coat); avoid contact with water and air

Boiling Point
Varies with concentration and solvent; n-Butyl lithium decomposes before boiling point can be reached in open air

Auto Ignition Temperature
>23C (pyrophoric in air)

Manufacturing Process
Reaction of butyl chloride with lithium metal in hydrocarbon solvent

Disposal Method
Neutralize cautiously and dispose in accordance with local, state, and federal regulations

Regulatory Information
Complies with relevant Indian chemical regulations (specific details depend on application)

Hazard Class
Class 4.2 (Substances liable to spontaneous combustion), UN No. 3394

Stability
Stable under recommended storage conditions (inert atmosphere, dry, sealed); decomposes with air/moisture contact

N Butyl Lithium Trade Information

Minimum Order Quantity
100 Kilograms

Supply Ability
500 Kilograms Per Day

Delivery Time
4 Days

About N Butyl Lithium

Product: N-Butyl Lithium 2.5M in Hexane / 1.6M in Hexane

Cas.No:109-72-8

Molecular Weight: 64.06

Density 0.693 g/mL at 25 deg C

Concentration 2.5 M in hexanes, Cyclo hexane,

Analysis: sec-Butanol Titration

Essential Reactivity for Precision Synthesis

N-Butyl Lithiums profound reactivity enables complex deprotonation, metalation, and polymerization processes that are crucial in advanced chemical manufacturing. Its strong nucleophilicity and basicity make it a preferred reagent for laboratory and industrial settings, helping produce high-value pharmaceutical intermediates and specialty chemicals with exceptional selectivity and efficiency.

Safe Handling and Storage

Due to its pyrophoric nature, n-butyl lithium is handled and stored exclusively under an inert atmosphere, typically nitrogen or argon. Proper personal protective equipmentgloves, goggles, lab coatsare mandatory to prevent accidental ignition or hazardous reactions. The liquid is packed in sealed, inert gas-filled bottles or drums, and must be kept away from moisture and air to maintain stability and safety.

Versatile Applications Across Industries

N-Butyl Lithium plays an indispensable role in organic synthesis, from academic research to industrial-scale production. Its robust performance as a strong base and initiator supports the development of pharmaceuticals, advanced polymers, and specialty compounds, ensuring efficiency and reliability in processes that demand precise and controlled reactivity.

FAQs of N Butyl Lithium:

Q: How should n-butyl lithium be safely handled and stored?

A: N-Butyl Lithium must always be handled in a dry, inert atmosphere (such as nitrogen or argon) to avoid dangerous reactions with air or moisture. It should be stored tightly sealed in its original packaging, away from any sources of heat, moisture, or open flame. Always use proper PPE, including gloves, eye protection, and lab coats.

Q: What is the typical usage of n-butyl lithium in laboratories and industry?

A: N-Butyl Lithium is primarily used as a strong base and nucleophile in organic synthesis, facilitating deprotonation, metalation, and polymerization reactions. It is essential for the preparation of pharmaceutical intermediates, specialty chemicals, and in organometallic laboratory research.

Q: When is n-butyl lithium most beneficial in chemical processes?

A: This reagent is particularly valuable when high selectivity and reactivity are required, such as during the initiation of polymerizations, synthesis of organometallic compounds, or precise deprotonation of sensitive substrates. Its effectiveness greatly benefits laboratories and industries focusing on advanced or custom chemical synthesis.

Q: Where does n-butyl lithium find its main applications?

A: The compound is widely used in research laboratories, pharmaceutical manufacturing, specialty chemical production, and polymer industries. It is distributed and supplied across India and often handled by trained chemists or technicians in controlled environments.

Q: What is the process for manufacturing n-butyl lithium?

A: N-butyl lithium is manufactured by reacting butyl chloride with lithium metal in a hydrocarbon solvent, such as hexane or heptane. This process is carefully controlled under anhydrous, inert conditions to prevent side reactions and ensure product purity.

Q: How is n-butyl lithium disposed of safely after use?

A: Disposal requires neutralization by cautious and controlled methods, strictly following local, state, and federal hazardous waste regulations. It should never be poured down the drain or exposed to air or water, and disposal is best conducted by qualified personnel in a licensed facility.

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